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Targets Recommended: SARS-CoV

抑制剂 & 化合物

化合物库

212

重组蛋白

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Cat. No.	Product Name
L1710	抗COVID-19化合物库		1133 compounds
	1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合，可用于高通量和高内涵筛选；

化合物库

抗COVID-19化合物库

Cat.No: L1710

Compounds: 1133

Cat. No.	Product Name	Target	Signaling Pathways
T78704	PLpro/RBD-IN-1	SARS-CoV	Microbiology/Virology
	PLpro/RBD-IN-1 (化合物 5) 为 SARS-CoV-2 PLpro 与刺突蛋白 RBD (spike protein Receptor Binding Domain) 的双重抑制剂，其 IC50 值分别为7.197 μM 和8.673 μM。
T36876	SBP1
	Human ACE2 receptor-derived 23-amino acid peptide. Binds receptor binding domain (RBD) of insect-derived SARS-CoV-2 spike protein (KD = 1.3 μM for N-terminal biotinylated, insect-derived spike protein RBD; see Zhang et al preprint publication). Please note - unpublished, in-house data suggests approximately 75-fold lower affinity for insect-derived SARS-CoV-2 RBD than reported by Zhang et al.
T68310	CPD7
	CPD7 is a novel non-RBD binding modulator to inhibit SARS-CoV-2 by prohibiting the conformational change of the spike (S) protein.
T71989	CPD7 HCl
	CPD7 HCl is a novel non-RBD binding modulator to inhibit SARS-CoV-2 by prohibiting the conformational change of the spike (S) protein.
T36877	SBP1-FITC SBP1-FITC
	Fluorescently labelled peptide derived from human ACE2 (SBP1, Cat. No. 7233). Composed of SBP1 conjugated to FITC (Fluorescein-5-isothiocyanate; Cat. No. 5440). SBP1 binds receptor binding domain (RBD) of insect-derived SARS-CoV-2 spike protein (KD = 1.3 μM for N-terminal biotinylated, insect-derived spike protein RBD; see Zhang et al preprint publication). Please note - unpublished, in-house data suggests SBP1 has approximately 75-fold lower affinity for insect-derived SARS-CoV-2 RBD than repo...
T69252	CPD26
	CPD26 is a novel non-RBD binding modulator to inhibit SARS-CoV-2 by prohibiting the conformational change of the spike (S) protein.
T36655	Anti-Spike-RBD mAb
	Anti-Spike-RBD mAb is a CHO cell derived human monoclonal IgG1 antibody. Blocking the interaction of spike protein and ACE2 is a potential therapeutic approach for SARS-CoV-2 treatment[1]. [1]. Chunyan Wang, et al. A Human Monoclonal Antibody Blocking SARS-CoV-2 Infection. Nat Commun. 2020 May 4;11(1):2251.
T76923	Beludavimab
	Beludavimab (BMS 4182137; VIR 7832) 是一种针对 SARS-CoV-2刺突糖蛋白的单克隆抗体。Beludavimab 与重组刺突蛋白受体结合域 (S-RBD) 结合，EC50值为 14.9 ng/mL，Kd 为 0.21 nM。
T76904	Amubarvimab
	Amubarvimab (BRII-196) 是一种人IgG1mAb，可结合刺突蛋白受体结合域 (RBD) 上的非竞争表位，KD 为 5.88 nM。Amubarvimab 可有效中和 SARS-CoV-2 变异体。
T74424	Masavibart
	Masavibart (ZRC3308-A7) 是一种靶向SARS-CoV-2的单克隆抗体 (IgG1 型)。Masavibart 对SARS-CoV-2穗状蛋白的RBD 上的非竞争性表位显示出良好的结合亲和力。Masavibart 可按 1:1 与ZRC3308-B10 联合使用，对 COVID-19 的预防以及尚未发展为严重疾病的早期 COVID-19 有效。
T74425	Nepuvibart
	Nepuvibart (ZRC3308-B10) 是一种靶向 SARS-CoV-2的单克隆抗体 (IgG1 型)。Nepuvibart 对 SARS-CoV-2穗状蛋白的 RBD 上的非竞争性表位显示出良好的结合亲和力。Nepuvibart 可按 1:1 与 ZRC3308-A7 联合使用，对 COVID-19 的预防以及尚未发展为严重疾病的早期 COVID-19 有效。
T76270	SARS-CoV-2-IN-34
	SARS-CoV-2-IN-34 (S-20-1) 是一种可穿透血脑屏障的 pan-coronavirus (CoV) fusion 抑制剂，具有广谱抑制活性。它能有效抑制伪型和真型 SARS-CoV-2 以及其变体 (VOCs) 的感染。SARS-CoV-2-IN-34 对 SARS-CoV-2 的 S1 和 S2 蛋白中的 HR1 和 RBD 结构域显示出高度亲和性，适用于感染研究。

化合物

Synonym: SBP1-FITC

Anti-Spike-RBD mAb

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00402	MERS-CoV Spike/RBD Protein fragment (aa 367-606, His) cov spike Protein, MERS-CoV,coronavirus	MERS-CoV	Baculovirus Insect Cells
	MERS-CoV Spike/RBD Protein fragment (aa 367-606, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 27.7 kDa and the accession number is K0BRG7.
TMPY-03574	MERS-CoV Spike/S1 Protein (aa 1-725, His) coronavirus spike Protein, MERS-CoV,corona...	MERS-CoV	HEK293 Cells
	MERS-CoV Spike/S1 Protein (aa 1-725, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 79.9 kDa and the accession number is K0BRG7.
TMPY-03512	MERS-CoV Spike/S2 Protein (aa 726-1296, His) RBD Prote,coronavirus s1 Protein, MERS-CoV...	MERS-CoV	Baculovirus Insect Cells
	MERS-CoV Spike/S2 Protein (aa 726-1296, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 63.84 kDa and the accession number is K0BRG7.
TMPY-03661	MERS-CoV Spike Protein (S1+S2 ECD, aa 1-1297, His) coronavirus spike Protein, MERS-CoV,ncov <...	MERS-CoV	Baculovirus Insect Cells
	MERS-CoV Spike Protein (S1+S2 ECD, aa 1-1297, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 44.10 kDa and the accession number is K0BRG7.
TMPK-00911	SARS Spike RBD Protein (His & Avi) S protein RBD,Spike protein	SARS	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike RBD Protein (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27.9 kDa and the accession number is P59594.
TMPK-00912	SARS Spike RBD Protein (His & Avi), Biotinylated S glycoprotein RBD,S protein ...	SARS	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike RBD Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27.9 kDa and the accession number...
TMPK-00439	SARS-COV-2 Spike RBD Protein (His & Avi), Biotinylated S protein RBD,S glycoprotein ...	SARS-CoV-2	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike RBD Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27 kDa and the accession nu...
TMPK-00434	SARS-COV-2 Spike RBD Protein (hFc & Avi), Biotinylated S protein RBD,S glycoprotein ...	SARS-CoV-2	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike RBD Protein (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 51.7 kDa and the accession ...
TMPK-00437	SARS-COV-2 Spike RBD Protein (His & Avi) S glycoprotein RBD,Spike prot...	SARS-CoV-2	HEK293 Cells
	The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike RBD Protein (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27 kDa and the accession number is A0A6G7...
TMPY-05817	SARS-CoV Spike/RBD Protein (His), Biotinylated ncov spike Protein, SARS,novel coronavirus...	SARS	Baculovirus Insect Cells
	SARS-CoV Spike/RBD Protein (His), Biotinylated is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is Q5DIC5.
TMPY-05701	SARS-CoV Spike/RBD Protein (mFc) ncov spike Protein, SARS,nove,ncov s2 ...	SARS	HEK293 Cells
	SARS-CoV Spike/RBD Protein (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 51.40 kDa and the accession number is Q5DIC5.
TMPY-06204	SARS-CoV (Isolate Tor2) Spike RBD Protein (His & Avi), Biotinylated ncov spike Protein, SARS,ncov RBD...	SARS	HEK293 Cells
	SARS-CoV (Isolate Tor2) Spike RBD Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.4 kDa and the accession number is NP_828851.1.
TMPY-03224	SARS-CoV Spike/RBD Protein (His) ncov s2 Protein, SARS,cov spike Protei...	SARS	Baculovirus Insect Cells
	SARS-CoV Spike/RBD Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is Q5DIC5.
TMPY-04177	SARS-CoV Spike/RBD Protein (rFc) cov spike Protein, SARS,ncov s1 Protei...	SARS	Baculovirus Insect Cells
	SARS-CoV Spike/RBD Protein (rFc) is expressed in Baculovirus insect cells with rFc tag. The predicted molecular weight is 50.2 kDa and the accession number is Q5DIC5.
TMPY-06372	SARS-CoV Spike RBD Protein (mFc), Biotinylated ncov spike Protein, SARS,cov spike	SARS	HEK293 Cells
	SARS-CoV Spike RBD Protein (mFc), Biotinylated is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 51.49 kDa and the accession number is AAX16192.1.
TMPY-05818	MERS-CoV Spike/RBD Protein fragment (aa 367-606, His), Biotinylated ncov s1 Protein, MERS-CoV,ncov RBD Pro...	MERS-CoV	Baculovirus Insect Cells
	MERS-CoV Spike/RBD Protein fragment (aa 367-606, His), Biotinylated is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 27.7 kDa and the accession number is K0BRG7.
TMPY-03228	MERS-CoV Spike/RBD Protein fragment (aa 367-606, rFc) coronavirus s2 Protein, MERS-CoV,ncov RBD ...	MERS-CoV	Baculovirus Insect Cells
	MERS-CoV Spike/RBD Protein fragment (aa 367-606, rFc) is expressed in Baculovirus insect cells with rFc tag. The predicted molecular weight is 51.5 kDa and the accession number is K0BRG7.
TMPY-06176	SARS-CoV (Isolate Tor2) Spike S1+S2 Protein (S577A, His), Biotinylated nove,ncov spike Protein, SARS,coronavirus ...	SARS	Baculovirus Insect Cells
	SARS-CoV (Isolate Tor2) Spike S1+S2 Protein (S577A, His), Biotinylated is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 132.58 kDa and the accession number is NP_828851.1.
TMPY-03988	SARS-CoV Spike/S1 Protein (His) ncov RBD Protein, SARS,nove,ncov s1 Pr...	SARS	Baculovirus Insect Cells
	SARS-CoV Spike/S1 Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 74.4 kDa and the accession number is Q5DIC5.
TMPY-05699	SARS-CoV Spike/S1 Protein (His), Biotinylated ncov s1 Protein, SARS,coronavirus s2 Protein	SARS	Baculovirus Insect Cells
	SARS-CoV Spike/S1 Protein (His), Biotinylated is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 74.4 kDa and the accession number is Q5DIC5.
TMPY-05702	SARS-CoV Spike/S1 Protein (mFc) coronavirus spike Protein, SARS,coronaviru...	SARS	HEK293 Cells
	SARS-CoV Spike/S1 Protein (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 99.40 kDa and the accession number is Q5DIC5.
TMPY-05718	SARS-CoV (Isolate Tor2) Spike S1+S2 ECD Protein (S577A, His) ncov s2 Protein, SARS,nove,coronavirus spike	SARS	Baculovirus Insect Cells
	SARS-CoV (Isolate Tor2) Spike S1+S2 ECD Protein (S577A, His) is expressed in Baculovirus insect cells. The predicted molecular weight is 132.58 kDa and the accession number is NP_828851.1.
TMPY-05722	SARS-CoV Spike S2 Protein (His) coronavirus spike Protein, SARS,ncov s2	SARS	Baculovirus Insect Cells
	SARS-CoV Spike S2 Protein (His) is expressed in Baculovirus insect cells. The predicted molecular weight is 59.65 kDa and the accession number is NP_828851.1.
TMPY-06225	MERS-CoV Spike Protein (aa 367-606, His & Avi), Biotinylated ncov s1 Protein, MERS-CoV,ncov s2 Protein,...	MERS-CoV	HEK293 Cells
	MERS-CoV Spike Protein (aa 367-606, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 29.6 kDa and the accession number is K0BRG7.
TMPY-06170	MERS-CoV Spike S1+S2 Protein (aa 1-1297, His), Biotinylated coronavirus spike Protein, MERS-CoV,corona...	MERS-CoV	Baculovirus Insect Cells
	MERS-CoV Spike S1+S2 Protein (aa 1-1297, His), Biotinylated is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 142.52 kDa and the accession number is K0BRG7.
TMPY-05679	SARS-CoV-2 Spike RBD Protein (hFc)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (hFc) is expressed in HEK293 mammalian cells. The predicted molecular weight is 51.8 kDa and the accession number is A0A6G7K2L4.
TMPY-05681	SARS-CoV-2 Spike RBD Protein (rFc)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (rFc) is expressed in HEK293 mammalian cells. The predicted molecular weight is 50.3 kDa and the accession number is A0A6G7K2L4.
TMPY-05663	SARS-CoV-2 Spike RBD Protein (mFc)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (mFc) is expressed in HEK293 mammalian cells. The predicted molecular weight is 51.5 kDa and the accession number is A0A6G7K2L4.
TMPY-05668	SARS-CoV-2 Spike RBD Protein (His)	SARS-CoV-2	Baculovirus Insect Cells
	SARS-CoV-2 Spike RBD Protein (His) is expressed in Baculovirus insect cells. The predicted molecular weight is 26.54 kDa and the accession number is A0A6G7K2L4.
TMPY-05975	SARS-CoV-2 Spike RBD Protein (P521S, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (P521S, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.5 kDa and the accession number is A0A6G7K2L4.
TMPY-05963	SARS-CoV-2 Spike RBD Protein (A522V, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (A522V, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.6 kDa and the accession number is A0A6G7K2L4.
TMPY-05965	SARS-CoV-2 Spike RBD Protein (A372S, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (A372S, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.6 kDa and the accession number is A0A6G7K2L4.
TMPY-05706	SARS-CoV-2 Spike RBD Protein (A435S, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (A435S, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.56 kDa and the accession number is A0A6G7K2L4.
TMPY-06041	SARS-CoV-2 Spike RBD Protein (K458Q, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (K458Q, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.5 kDa and the accession number is A0A6G7K2L4.
TMPY-06000	SARS-CoV-2 Spike RBD Protein (P479S, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (P479S, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.5 kDa and the accession number is A0A6G7K2L4.
TMPY-05724	SARS-CoV-2 Spike RBD Protein (G476S, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (G476S, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.57 kDa and the accession number is A0A6G7K2L4.
TMPY-05980	SARS-CoV-2 Spike RBD Protein (Q409E, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (Q409E, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.5 kDa and the accession number is A0A6G7K2L4.
TMPY-06050	SARS-CoV-2 Spike RBD Protein (Y453F, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (Y453F, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.5 kDa and the accession number is A0A6G7K2L4.
TMPY-05990	SARS-CoV-2 Spike RBD Protein (S477I, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (S477I, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.6 kDa and the accession number is A0A6G7K2L4.
TMPY-06152	SARS-CoV-2 Spike RBD Protein (N501Y, rFc)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (N501Y, rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 50.4 kDa and the accession number is A0A6G7K2L4.
TMPY-06232	SARS-CoV-2 Spike RBD Protein (A475T, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (A475T, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is A0A6G7K2L4.
TMPY-06241	SARS-CoV-2 Spike RBD Protein (Y449H, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (Y449H, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is A0A6G7K2L4.
TMPY-06229	SARS-CoV-2 Spike RBD Protein (E471A, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (E471A, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is A0A6G7K2L4.
TMPY-06153	SARS-CoV-2 Spike RBD Protein (E484K, rFc)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (E484K, rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 50.4 kDa and the accession number is A0A6G7K2L4.
TMPY-06238	SARS-CoV-2 Spike RBD Protein (E484A, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (E484A, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is A0A6G7K2L4.
TMPY-06235	SARS-CoV-2 Spike RBD Protein (P479L, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (P479L, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is A0A6G7K2L4.
TMPY-06234	SARS-CoV-2 Spike RBD Protein (S477G, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (S477G, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is A0A6G7K2L4.
TMPY-06072	SARS-CoV-2 Spike RBD Protein (L455F, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (L455F, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.6 kDa and the accession number is A0A6G7K2L4.
TMPY-05966	SARS-CoV-2 Spike RBD Protein (A520S, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (A520S, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.57 kDa and the accession number is A0A6G7K2L4.
TMPY-06068	SARS-CoV-2 Spike RBD Protein (N501Y, His)	SARS-CoV-2	HEK293 Cells
	SARS-CoV-2 Spike RBD Protein (N501Y, His) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.6 kDa and the accession number is A0A6G7K2L4.
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重组蛋白

MERS-CoV Spike/RBD Protein fragment (aa 367-606, His)

Cat.No: TMPY-00402

Species: MERS-CoV

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